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Novel perspectives on non-canonical inflammasome activation

Inflammasomes are cytosolic multi-protein complexes that regulate the secretion of the proinflammatory cytokines, IL-1β and IL-18, and induce pyroptosis, an inflammatory form of cell death. The NLRP3 inflammasome is the most well-characterized member of this family and functions by sensing intracell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunotargets Ther
Hauptverfasser: Diamond, Catherine Emma, Khameneh, Hanif Javanmard, Brough, David, Mortellaro, Alessandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918253/
https://ncbi.nlm.nih.gov/pubmed/27471719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S57976
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