Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation

Deregulation of inflammasome activation was recently identified to be involved in the pathogenesis of various inflammatory diseases. Although macrolide antibiotics display well described immunomodulatory properties, presumably involved in their clinical effects, their impact on inflammasome activati...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Gualdoni, Guido A., Lingscheid, Tilman, Schmetterer, Klaus G., Hennig, Annika, Steinberger, Peter, Zlabinger, Gerhard J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495566/
https://ncbi.nlm.nih.gov/pubmed/26152605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12016
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