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Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation

Deregulation of inflammasome activation was recently identified to be involved in the pathogenesis of various inflammatory diseases. Although macrolide antibiotics display well described immunomodulatory properties, presumably involved in their clinical effects, their impact on inflammasome activati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gualdoni, Guido A., Lingscheid, Tilman, Schmetterer, Klaus G., Hennig, Annika, Steinberger, Peter, Zlabinger, Gerhard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495566/
https://ncbi.nlm.nih.gov/pubmed/26152605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12016
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