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Convergent and divergent sequence evolution in the surface envelope glycoprotein of human immunodeficiency virus type 1 within a single infected patient.

In an investigation of the evolution of the third hypervariable loop of gp120 (V3), the principal neutralization determinant of human immunodeficiency virus type 1, we have analyzed 89 V3 sequences of plasma viral RNA purified from peripheral blood samples donated over 7 years by an infected hemophi...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Holmes, E C, Zhang, L Q, Simmonds, P, Ludlam, C A, Brown, A J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1594583/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.11.4835
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