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Length polymorphism within the second variable region of the human immunodeficiency virus type 1 envelope glycoprotein affects accessibility of the receptor binding site.

Sequential mutations were introduced into the V2 region of human immunodeficiency virus (HIV) type 1 HXB2, affecting the length, charge, and number of potential glycosylation sites. The insertions had no effect on cytopathicity or on the ability of virus to replicate in peripheral blood mononuclear...

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Publicado no:J Virol
Principais autores: Fox, D G, Balfe, P, Palmer, C P, May, J C, Arnold, C, McKeating, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985413/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.759-765.1997
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