Progressive impairment of Ca(V)1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder that is typically fatal within 3–5 years of diagnosis. While motoneuron death is the defining characteristic of ALS, the events that underlie its pathology are not restricted to the nervous system. In this r...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Skelet Muscle
Egile Nagusiak: Beqollari, Donald, Romberg, Christin F., Dobrowolny, Gabriella, Martini, Martina, Voss, Andrew A., Musarò, Antonio, Bannister, Roger A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918102/
https://ncbi.nlm.nih.gov/pubmed/27340545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-016-0094-6
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