Progressive impairment of Ca(V)1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder that is typically fatal within 3–5 years of diagnosis. While motoneuron death is the defining characteristic of ALS, the events that underlie its pathology are not restricted to the nervous system. In this r...

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Bibliographic Details
Published in:Skelet Muscle
Main Authors: Beqollari, Donald, Romberg, Christin F., Dobrowolny, Gabriella, Martini, Martina, Voss, Andrew A., Musarò, Antonio, Bannister, Roger A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918102/
https://ncbi.nlm.nih.gov/pubmed/27340545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-016-0094-6
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