TWEAK-binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti-TNF therapy

BACKGROUND: TNF weakly inducer of apoptosis (TWEAK) is member of the TNF ligand superfamily. Various data support that TWEAK produced by synovial macrophages may contribute to synovitis observed in psoriatic arthritis (PsoA). In PsoA, anti-TNF therapy has been successful in agreement with the key ro...

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Vydáno v:J Transl Med
Hlavní autoři: Guis, Sandrine, Berbis, Philippe, Stephan, Delphine, Bertin, Daniel, Amatore, Florent, Balandraud, Nathalie, Lesavre, Nathalie, Desplat-Jégo, Sophie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917994/
https://ncbi.nlm.nih.gov/pubmed/27338143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0923-8
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