TWEAK-binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti-TNF therapy

BACKGROUND: TNF weakly inducer of apoptosis (TWEAK) is member of the TNF ligand superfamily. Various data support that TWEAK produced by synovial macrophages may contribute to synovitis observed in psoriatic arthritis (PsoA). In PsoA, anti-TNF therapy has been successful in agreement with the key ro...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Transl Med
Main Authors: Guis, Sandrine, Berbis, Philippe, Stephan, Delphine, Bertin, Daniel, Amatore, Florent, Balandraud, Nathalie, Lesavre, Nathalie, Desplat-Jégo, Sophie
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917994/
https://ncbi.nlm.nih.gov/pubmed/27338143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0923-8
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