TWEAK-binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti-TNF therapy

BACKGROUND: TNF weakly inducer of apoptosis (TWEAK) is member of the TNF ligand superfamily. Various data support that TWEAK produced by synovial macrophages may contribute to synovitis observed in psoriatic arthritis (PsoA). In PsoA, anti-TNF therapy has been successful in agreement with the key ro...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Guis, Sandrine, Berbis, Philippe, Stephan, Delphine, Bertin, Daniel, Amatore, Florent, Balandraud, Nathalie, Lesavre, Nathalie, Desplat-Jégo, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917994/
https://ncbi.nlm.nih.gov/pubmed/27338143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0923-8
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