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TWEAK-binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti-TNF therapy

BACKGROUND: TNF weakly inducer of apoptosis (TWEAK) is member of the TNF ligand superfamily. Various data support that TWEAK produced by synovial macrophages may contribute to synovitis observed in psoriatic arthritis (PsoA). In PsoA, anti-TNF therapy has been successful in agreement with the key ro...

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Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Guis, Sandrine, Berbis, Philippe, Stephan, Delphine, Bertin, Daniel, Amatore, Florent, Balandraud, Nathalie, Lesavre, Nathalie, Desplat-Jégo, Sophie
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917994/
https://ncbi.nlm.nih.gov/pubmed/27338143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0923-8
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