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A randomized phase l pharmacokinetic study comparing SB4 and etanercept reference product (Enbrel®) in healthy subjects

AIMS: SB4 has been developed as a biosimilar of etanercept. The primary objective of the present study was to demonstrate the pharmacokinetic (PK) equivalence between SB4 and European Union ‐sourced etanercept (EU‐ETN), SB4 and United States‐sourced etanercept (US‐ETN), and EU‐ETN and US‐ETN. The sa...

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Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Lee, Yoon Jung, Shin, Donghoon, Kim, Youngdoe, Kang, Jungwon, Gauliard, Anke, Fuhr, Rainard
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917797/
https://ncbi.nlm.nih.gov/pubmed/26972584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12929
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