Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition

The human sirtuins (SIRT1–SIRT7) enzymes are a highly conserved family of NAD(+)-dependent histone deacetylases, which play a critical role in the regulation of a large number of metabolic pathways involved in stress response and aging. Cancer is an age-associated disease, and sirtuins may have a co...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Palmirotta, Raffaele, Cives, Mauro, Della-Morte, David, Capuani, Barbara, Lauro, Davide, Guadagni, Fiorella, Silvestris, Franco
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917709/
https://ncbi.nlm.nih.gov/pubmed/27379175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3031459
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