Transcription factor Six2 mediates the protection of GDNF on 6-OHDA lesioned dopaminergic neurons by regulating Smurf1 expression

Glial cell line-derived neurotrophic factor (GDNF) has strong neuroprotective and neurorestorative effects on dopaminergic (DA) neurons in the substantia nigra (SN); however, the underlying molecular mechanisms remain to be fully elucidated. In this study, we found that the expression level of trans...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gao, J, Kang, X-y, Sun, S, Li, L, Zhang, B-l, Li, Y-q, Gao, D-s
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917658/
https://ncbi.nlm.nih.gov/pubmed/27148690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.120
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