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MicroRNA-21 promotes phosphatase gene and protein kinase B/phosphatidylinositol 3-kinase expression in colorectal cancer

AIM: To explore the regulatory mechanism of the target gene of microRNA-21 (miR-21), phosphatase gene (PTEN), and its downstream proteins, protein kinase B (AKT) and phosphatidylinositol 3-kinase (PI3K), in colorectal cancer (CRC) cells. METHODS: Quantitative real-time PCR (qRT-PCR) and Western blot...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Sheng, Wei-Zhong, Chen, Yu-Sheng, Tu, Chuan-Tao, He, Juan, Zhang, Bo, Gao, Wei-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917613/
https://ncbi.nlm.nih.gov/pubmed/27350731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i24.5532
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