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Differential Ascending and Descending Aortic Mechanics Parallel Aneurysmal Propensity in a Mouse Model of Marfan Syndrome

Marfan syndrome (MFS) is a multi-system connective tissue disorder that results from mutations to the gene that codes the elastin-associated glycoprotein fibrillin-1. Although elastic fibers are compromised throughout the arterial tree, the most severe phenotype manifests in the ascending aorta. By...

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書目詳細資料
發表在:J Biomech
Main Authors: Bellini, C., Korneva, A., Zilberberg, L., Ramirez, F., Rifkin, D.B., Humphrey, J.D.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917480/
https://ncbi.nlm.nih.gov/pubmed/26755343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2015.11.059
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