Elucidating Proteoform Families from Proteoform Intact-Mass and Lysine-Count Measurements

[Image: see text] Proteomics is presently dominated by the “bottom-up” strategy, in which proteins are enzymatically digested into peptides for mass spectrometric identification. Although this approach is highly effective at identifying large numbers of proteins present in complex samples, the diges...

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Udgivet i:J Proteome Res
Main Authors: Shortreed, Michael R., Frey, Brian L., Scalf, Mark, Knoener, Rachel A., Cesnik, Anthony J., Smith, Lloyd M.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2016
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917391/
https://ncbi.nlm.nih.gov/pubmed/26941048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b01090
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