Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABA(A) Receptors: Functional Characteristics and Molecular Mechanism

Extracts of the pepper plant kava (Piper methysticum) are effective in alleviating anxiety in clinical trials. Despite the long-standing therapeutic interest in kava, the molecular target(s) of the pharmacologically active constituents, kavalactones have not been established. γ-Aminobutyric acid typ...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Chua, Han Chow, Christensen, Emilie T. H., Hoestgaard-Jensen, Kirsten, Hartiadi, Leonny Y., Ramzan, Iqbal, Jensen, Anders A., Absalom, Nathan L., Chebib, Mary
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917254/
https://ncbi.nlm.nih.gov/pubmed/27332705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157700
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