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A Human Trypanosome Suppresses CD8(+) T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4(+) Foxp3(+) T Cells

Although CD4(+) Foxp3(+) T cells are largely described in the regulation of CD4(+) T cell responses, their role in the suppression of CD8(+) T cell priming is much less clear. Because the induction of CD8(+) T cells during experimental infection with Trypanosoma cruzi is remarkably delayed and subop...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ersching, Jonatan, Basso, Alexandre Salgado, Kalich, Vera Lucia Garcia, Bortoluci, Karina Ramalho, Rodrigues, Maurício M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917094/
https://ncbi.nlm.nih.gov/pubmed/27332899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005698
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