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Microsecond Simulations of the Diphtheria Toxin Translocation Domain in Association with Anionic Lipid Bilayers

Diphtheria toxin translocation (T) domain undergoes conformational changes in acidic solution and associates with the lipid membranes, followed by refolding and transmembrane insertion of two nonpolar helices. This process is an essential step in delivery of the toxic catalytic domain of the diphthe...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Flores-Canales, Jose C., Maria, Kurnikova
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916650/
https://ncbi.nlm.nih.gov/pubmed/26305016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b07909
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