Staphylococcus aureus Coordinates Leukocidin Expression and Pathogenesis by Sensing Metabolic Fluxes via RpiRc

Staphylococcus aureus is a formidable human pathogen that uses secreted cytolytic factors to injure immune cells and promote infection of its host. Of these proteins, the bicomponent family of pore-forming leukocidins play critical roles in S. aureus pathogenesis. The regulatory mechanisms governing...

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Udgivet i:mBio
Main Authors: Balasubramanian, Divya, Ohneck, Elizabeth A., Chapman, Jessica, Weiss, Andy, Kim, Min Kyung, Reyes-Robles, Tamara, Zhong, Judy, Shaw, Lindsey N., Lun, Desmond S., Ueberheide, Beatrix, Shopsin, Bo, Torres, Victor J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916384/
https://ncbi.nlm.nih.gov/pubmed/27329753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00818-16
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