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E-Flux2 and SPOT: Validated Methods for Inferring Intracellular Metabolic Flux Distributions from Transcriptomic Data

BACKGROUND: Several methods have been developed to predict system-wide and condition-specific intracellular metabolic fluxes by integrating transcriptomic data with genome-scale metabolic models. While powerful in many settings, existing methods have several shortcomings, and it is unclear which met...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Min Kyung, Lane, Anatoliy, Kelley, James J., Lun, Desmond S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915706/
https://ncbi.nlm.nih.gov/pubmed/27327084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157101
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