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Nucleosome disassembly during human non-homologous end joining followed by concerted HIRA- and CAF-1-dependent reassembly

The cell achieves DNA double-strand break (DSB) repair in the context of chromatin structure. However, the mechanisms used to expose DSBs to the repair machinery and to restore the chromatin organization after repair remain elusive. Here we show that induction of a DSB in human cells causes local nu...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Li, Xuan, Tyler, Jessica K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915809/
https://ncbi.nlm.nih.gov/pubmed/27269284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15129
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