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A Mechanistic Beta-Binomial Probability Model for mRNA Sequencing Data

A main application for mRNA sequencing (mRNAseq) is determining lists of differentially-expressed genes (DEGs) between two or more conditions. Several software packages exist to produce DEGs from mRNAseq data, but they typically yield different DEGs, sometimes markedly so. The underlying probability...

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Pubblicato in:PLoS One
Autori principali: Smith, Gregory R., Birtwistle, Marc R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915702/
https://ncbi.nlm.nih.gov/pubmed/27326762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157828
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