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Mutations in the catalytic subunit of cAMP-dependent protein kinase result in unregulated biological activity.

Mutations were identified in the catalytic subunit (C) of the cAMP-dependent protein kinase (EC 2.7.1.37) that block inactivation by regulatory subunit (R) without compromising catalytic activity. Randomly mutagenized mouse C expression vectors were screened functionally for clones that stimulated g...

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Bibliografische gegevens
Hoofdauteurs: Orellana, S A, McKnight, G S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1992
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC49156/
https://ncbi.nlm.nih.gov/pubmed/1584809
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