The Genetic Program of Pancreatic β-Cell Replication In Vivo

The molecular program underlying infrequent replication of pancreatic β-cells remains largely inaccessible. Using transgenic mice expressing green fluorescent protein in cycling cells, we sorted live, replicating β-cells and determined their transcriptome. Replicating β-cells upregulate hundreds of...

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Dettagli Bibliografici
Pubblicato in:Diabetes
Autori principali: Klochendler, Agnes, Caspi, Inbal, Corem, Noa, Moran, Maya, Friedlich, Oriel, Elgavish, Sharona, Nevo, Yuval, Helman, Aharon, Glaser, Benjamin, Eden, Amir, Itzkovitz, Shalev, Dor, Yuval
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2016
Soggetti:
Genetics/Genomes/Proteomics/Metabolomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915587/
https://ncbi.nlm.nih.gov/pubmed/26993067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0003
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