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γH2AX expression in cytological specimens as a biomarker of response to radiotherapy in solid malignancies
Many anticancer treatments, including radiotherapy, act by damaging DNA and hindering cell function and proliferation. H2AX is a histone protein directly associated with DNA that is phosphorylated to produce γH2AX that accumulates in foci in an early response to DNA double‐strand breaks, the most de...
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| Pubblicato in: | Diagn Cytopathol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914953/ https://ncbi.nlm.nih.gov/pubmed/26667983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dc.23396 |
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