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γH2AX expression in cytological specimens as a biomarker of response to radiotherapy in solid malignancies

Many anticancer treatments, including radiotherapy, act by damaging DNA and hindering cell function and proliferation. H2AX is a histone protein directly associated with DNA that is phosphorylated to produce γH2AX that accumulates in foci in an early response to DNA double‐strand breaks, the most de...

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Detaylı Bibliyografya
Yayımlandı:Diagn Cytopathol
Asıl Yazarlar: Shah, Ketan, Boghozian, Ramon A., Kartsonaki, Christiana, Shah, Ketan A., Vallis, Katherine A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914953/
https://ncbi.nlm.nih.gov/pubmed/26667983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dc.23396
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