Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis

Whether gene repositioning to the nuclear periphery during differentiation adds another layer of regulation to gene expression remains controversial. Here, we resolve this by manipulating gene positions through targeting the nuclear envelope transmembrane proteins (NETs) that direct their normal rep...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Robson, Michael I., de las Heras, Jose I., Czapiewski, Rafal, Lê Thành, Phú, Booth, Daniel G., Kelly, David A., Webb, Shaun, Kerr, Alastair R.W., Schirmer, Eric C.
Format: Artigo
Language:Inglês
Published: Cell Press 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914829/
https://ncbi.nlm.nih.gov/pubmed/27264872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.04.035
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