Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis

Whether gene repositioning to the nuclear periphery during differentiation adds another layer of regulation to gene expression remains controversial. Here, we resolve this by manipulating gene positions through targeting the nuclear envelope transmembrane proteins (NETs) that direct their normal rep...

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Vydáno v:Mol Cell
Hlavní autoři: Robson, Michael I., de las Heras, Jose I., Czapiewski, Rafal, Lê Thành, Phú, Booth, Daniel G., Kelly, David A., Webb, Shaun, Kerr, Alastair R.W., Schirmer, Eric C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914829/
https://ncbi.nlm.nih.gov/pubmed/27264872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.04.035
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