Expression of interleukin 1-inducible genes and production of interleukin 1 by aging human fibroblasts.
The interleukin 1 (IL-1)-inducible mRNAs for plasminogen activator inhibitor type 2, manganese superoxide dismutase, and urokinase are overexpressed in old (greater than 70% of life-span completed) but not in young (less than 40% of life-span completed) human foreskin fibroblasts. Furthermore, the a...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1992
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49147/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1584804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.10.4683 |
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