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Expression of interleukin 1-inducible genes and production of interleukin 1 by aging human fibroblasts.

The interleukin 1 (IL-1)-inducible mRNAs for plasminogen activator inhibitor type 2, manganese superoxide dismutase, and urokinase are overexpressed in old (greater than 70% of life-span completed) but not in young (less than 40% of life-span completed) human foreskin fibroblasts. Furthermore, the a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kumar, S, Millis, A J, Baglioni, C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49147/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1584804/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.10.4683
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