Expression of interleukin 1-inducible genes and production of interleukin 1 by aging human fibroblasts.

The interleukin 1 (IL-1)-inducible mRNAs for plasminogen activator inhibitor type 2, manganese superoxide dismutase, and urokinase are overexpressed in old (greater than 70% of life-span completed) but not in young (less than 40% of life-span completed) human foreskin fibroblasts. Furthermore, the a...

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Bibliographic Details
Main Authors: Kumar, S, Millis, A J, Baglioni, C
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC49147/
https://ncbi.nlm.nih.gov/pubmed/1584804
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