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In Vitro Analysis of the Interaction between Atovaquone and Proguanil against Liver Stage Malaria Parasites
The interaction between atovaquone and proguanil has never been studied against liver stage malaria, which is the main target of this drug combination when used for chemoprevention. Using human hepatocytes lacking cytochrome P450 activity, and thus avoiding proguanil metabolizing into potent cyclogu...
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| Vydáno v: | Antimicrob Agents Chemother |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914690/ https://ncbi.nlm.nih.gov/pubmed/26926628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01685-15 |
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