Antimalarial Activity of Small-Molecule Benzothiazole Hydrazones

We synthesized a new series of conjugated hydrazones that were found to be active against malaria parasite in vitro, as well as in vivo in a murine model. These hydrazones concentration-dependently chelated free iron and offered antimalarial activity. Upon screening of the synthesized hydrazones, co...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Sarkar, Souvik, Siddiqui, Asim A., Saha, Shubhra J., De, Rudranil, Mazumder, Somnath, Banerjee, Chinmoy, Iqbal, Mohd S., Nag, Shiladitya, Adhikari, Susanta, Bandyopadhyay, Uday
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914622/
https://ncbi.nlm.nih.gov/pubmed/27139466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01575-15
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