NMDA receptor-dependent LTD requires transient synaptic incorporation of Ca(2+)permeable AMPA receptors mediated by AKAP150-anchored PKA and calcineurin

Information processing in the brain requires multiple forms of synaptic plasticity that converge on regulation of NMDA and AMPA-type glutamate receptors (NMDAR, AMPAR), including long-term potentiation (LTP) and depression (LTD) and homeostatic scaling. In some cases, LTP and homeostatic plasticity...

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Gepubliceerd in:Neuron
Hoofdauteurs: Sanderson, Jennifer L., Gorski, Jessica A., Dell’Acqua, Mark L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914360/
https://ncbi.nlm.nih.gov/pubmed/26938443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.01.043
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