AKAP150-Anchored Calcineurin Regulates Synaptic Plasticity by Limiting Synaptic Incorporation of Ca(2+)-Permeable AMPA Receptors

AMPA receptors (AMPARs) are tetrameric ion channels assembled from GluA1–GluA4 subunits that mediate the majority of fast excitatory synaptic transmission in the brain. In the hippocampus, most synaptic AMPARs are composed of GluA1/2 or GluA2/3 with the GluA2 subunit preventing Ca(2+) influx. Howeve...

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Autores principales: Sanderson, Jennifer L., Gorski, Jessica A., Gibson, Emily S., Lam, Philip, Freund, Ronald K., Chick, Wallace S., Dell'Acqua, Mark L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2012
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504485/
https://ncbi.nlm.nih.gov/pubmed/23100425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3326-12.2012
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