AKAP150-Anchored Calcineurin Regulates Synaptic Plasticity by Limiting Synaptic Incorporation of Ca(2+)-Permeable AMPA Receptors

AMPA receptors (AMPARs) are tetrameric ion channels assembled from GluA1–GluA4 subunits that mediate the majority of fast excitatory synaptic transmission in the brain. In the hippocampus, most synaptic AMPARs are composed of GluA1/2 or GluA2/3 with the GluA2 subunit preventing Ca(2+) influx. Howeve...

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Main Authors: Sanderson, Jennifer L., Gorski, Jessica A., Gibson, Emily S., Lam, Philip, Freund, Ronald K., Chick, Wallace S., Dell'Acqua, Mark L.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2012
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504485/
https://ncbi.nlm.nih.gov/pubmed/23100425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3326-12.2012
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