Prognostic relevance of HER2/neu in acute lymphoblastic leukemia and induction of NK cell reactivity against primary ALL blasts by trastuzumab

The epidermal growth factor receptor HER2/neu is expressed on various cancers and represents a negative prognostic marker, but is also a target for the therapeutic monoclonal antibody Trastuzumab. In about 30% of cases, HER2/neu is expressed on acute lymphoblastic leukemia (ALL) cells and was propos...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Haen, Sebastian P., Schmiedel, Benjamin J., Rothfelder, Kathrin, Schmied, Bastian J., Dang, Truong-Minh, Mirza, Nora, Möhle, Robert, Kanz, Lothar, Vogel, Wichard, Salih, Helmut R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914338/
https://ncbi.nlm.nih.gov/pubmed/26887048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7344
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