Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction

Glioblastomas are resistant to many kinds of treatment, including chemotherapy, radiation and other adjuvant therapies. As(2)O(3) reportedly induces ROS generation in cells, suggesting it may be able to induce telomerase suppression and telomere dysfunction in glioblastoma cells. We show here that A...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cheng, Ye, Li, Yunqian, Ma, Chengyuan, Song, Yang, Xu, Haiyang, Yu, Hongquan, Xu, Songbai, Mu, Qingchun, Li, Haisong, Chen, Yong, Zhao, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914314/
https://ncbi.nlm.nih.gov/pubmed/26871293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7259
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