CD274/PD-L1 gene amplification and PD-L1 protein expression are common events in squamous cell carcinoma of the oral cavity

Immunomodulatory therapies, targeting the immune checkpoint receptor-ligand complex PD-1/PD-L1 have shown promising results in early phase clinical trials in solid malignancies, including carcinomas of the head and neck. In this context, PD-L1 protein expression has been proposed as a potentially va...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Straub, Melanie, Drecoll, Enken, Pfarr, Nicole, Weichert, Wilko, Langer, Rupert, Hapfelmeier, Alexander, Götz, Carolin, Wolff, Klaus-Dietrich, Kolk, Andreas, Specht, Katja
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914266/
https://ncbi.nlm.nih.gov/pubmed/26918453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7593
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