CCR5 deficiency accelerates lipopolysaccharide-induced astrogliosis, amyloid-beta deposit and impaired memory function

Chemokine receptors are implicated in inflammation and immune responses. Neuro-inflammation is associated with activation of astrocyte and amyloid-beta (Aβ) generations that lead to pathogenesis of Alzheimer disease (AD). Previous our study showed that deficiency of CC chemokine receptor 5 (CCR5) re...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Hwang, Chul Ju, Park, Mi Hee, Hwang, Jae Yeon, Kim, Ju Hwan, Yun, Na Young, Oh, Sang Yeon, Song, Ju Kyung, Seo, Hyun Ok, Kim, Yun-Bae, Hwang, Dae Yeon, Oh, Ki-Wan, Han, Sang-Bae, Hong, Jin Tae
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper: Pathology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914263/
https://ncbi.nlm.nih.gov/pubmed/26910914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7453
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