Memory Impairment in Estrogen Receptor α Knockout Mice Through Accumulation of Amyloid-β Peptides

Estrogen has been known to reduce the development of Alzheimer’s disease (AD). However, exact mechanisms are not clear. We investigated whether estrogen can increase amyloid-beta (Aβ) degradation and affects Aβ-induced memory impairment in an estrogen deficiency model. Estrogen receptor alpha (ERα)...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Hwang, Chul Ju, Yun, Hyung-Mun, Park, Kyung-Ran, Song, Ju Kyung, Seo, Hyun Ok, Hyun, Byung Kook, Choi, Dong Young, Yoo, Hwan-Soo, Oh, Ki-Wan, Hwang, Dae Yeun, Han, Sang-Bae, Hong, Jin Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510915/
https://ncbi.nlm.nih.gov/pubmed/25128029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8853-z
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