Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells

The xCT light chain of the cystine/glutamate transporter (system X(C)(−)) is of importance for the survival of triple-negative breast cancer (TNBC) cells. The MUC1-C transmembrane oncoprotein is aberrantly overexpressed in TNBC and, like xCT, has been linked to maintaining glutathione (GSH) levels a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hasegawa, Masanori, Takahashi, Hidekazu, Rajabi, Hasan, Alam, Maroof, Suzuki, Yozo, Yin, Li, Tagde, Ashujit, Maeda, Takahiro, Hiraki, Masayuki, Sukhatme, Vikas P., Kufe, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914246/
https://ncbi.nlm.nih.gov/pubmed/26930718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7598
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