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Valence tautomerism in synthetic models of cytochrome P450

CytP450s have a cysteine-bound heme cofactor that, in its as-isolated resting (oxidized) form, can be conclusively described as a ferric thiolate species. Unlike the native enzyme, most synthetic thiolate-bound ferric porphyrins are unstable in air unless the axial thiolate ligand is sterically prot...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Das, Pradip Kumar, Samanta, Subhra, McQuarters, Ashley B., Lehnert, Nicolai, Dey, Abhishek
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914151/
https://ncbi.nlm.nih.gov/pubmed/27302948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600525113
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