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Differential role of arginine mutations on the structure and functions of α-crystallin

BACKGROUND: α-Crystallin is a major protein of the eye lens in vertebrates. It is composed of two subunits, αA- and αB-crystallin. α-Crystallin is an oligomeric protein having these two subunits in 3:1 ratio. It belongs to small heat shock protein family and exhibits molecular chaperone function, wh...

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Publicado en:Biochim Biophys Acta
Main Authors: Panda, Alok Kumar, Nandi, Sandip Kumar, Chakraborty, Ayon, Nagaraj, Ram H., Biswas, Ashis
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914040/
https://ncbi.nlm.nih.gov/pubmed/26080000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2015.06.004
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