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Comparative toxicity and biodistribution of copper nanoparticles and cupric ions in rats

Despite widespread use and prospective biomedical applications of copper nanoparticles (Cu NPs), their biosafety issues and kinetics remain unclear. Thus, the aim of this study was to compare the detailed in vivo toxicity of Cu NPs and cupric ions (CuCl(2); Cu ions) after a single oral dose. We dete...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Lee, In-Chul, Ko, Je-Won, Park, Sung-Hyeuk, Lim, Je-Oh, Shin, In-Sik, Moon, Changjong, Kim, Sung-Hwan, Heo, Jeong-Doo, Kim, Jong-Choon
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913985/
https://ncbi.nlm.nih.gov/pubmed/27366066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S106346
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