Role of mitogen-activated protein kinases and nuclear factor-kappa B in 1,3-dichloro-2-propanol-induced hepatic injury

In this study, the potential hepatotoxicity of 1,3-dichloro-2-propanol and its hepatotoxic mechanisms in rats was investigated. The test chemical was administered orally to male rats at 0, 27.5, 55, and 110 mg/kg body weight. 1,3-Dichloro-2-propanol administration caused acute hepatotoxicity, as evi...

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Detalhes bibliográficos
Publicado no:Lab Anim Res
Main Authors: Lee, In-Chul, Lee, Sang-Min, Ko, Je-Won, Park, Sung-Hyeuk, Shin, In-Sik, Moon, Changjong, Kim, Sung-Ho, Kim, Jong-Choon
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Association for Laboratory Animal Science 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816994/
https://ncbi.nlm.nih.gov/pubmed/27051440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5625/lar.2016.32.1.24
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