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Endothelial Dysfunction in Human Diabetes is mediated by Wnt5a-JNK Signaling

OBJECTIVES: Endothelial dysfunction is linked to insulin resistance, inflammatory activation and increased cardiovascular risk in diabetes mellitus; however the mechanisms remain incompletely understood. Recent studies have identified pro-inflammatory signaling of Wnt5a through JNK as a regulator of...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Bretón-Romero, Rosa, Feng, Bihua, Holbrook, Monika, Farb, Melissa G., Fetterman, Jessica L., Linder, Erika A., Berk, Brittany D., Masaki, Nobuyuki, Weisbrod, Robert M., Inagaki, Elica, Gokce, Noyan, Fuster, Jose J., Walsh, Kenneth, Hamburg, Naomi M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913891/
https://ncbi.nlm.nih.gov/pubmed/26800561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306578
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