A CRISPR-Cas9 Gene Drive System Targeting Female Reproduction in the Malaria Mosquito vector Anopheles gambiae

Gene-drive systems that enable super-Mendelian inheritance of a transgene have the potential to modify insect populations over a timeframe of a few years [AU please provide a real estimate, this seems vague]. We describe CRISPR-Cas9 endonuclease constructs that function as gene-drive systems in Anop...

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Bibliografiske detaljer
Udgivet i:Nat Biotechnol
Main Authors: Hammond, Andrew, Galizi, Roberto, Kyrou, Kyros, Simoni, Alekos, Siniscalchi, Carla, Katsanos, Dimitris, Gribble, Matthew, Baker, Dean, Marois, Eric, Russell, Steven, Burt, Austin, Windbichler, Nikolai, Crisanti, Andrea, Nolan, Tony
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913862/
https://ncbi.nlm.nih.gov/pubmed/26641531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3439
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