Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice

Inositol hexakisphosphate kinases (IP6Ks), a family of enzymes found in all eukaryotes, are responsible for the synthesis of 5-diphosphoinositol pentakisphosphate (5-IP(7)) from inositol hexakisphosphate (IP(6)). Three isoforms of IP6Ks are found in mammals, and gene deletions of each isoform lead t...

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Publicat a:Cell Signal
Autors principals: Jadav, Rathan S., Kumar, Dharmika, Buwa, Natasha, Ganguli, Shubhra, Thampatty, Sitalakshmi R., Balasubramanian, Nagaraj, Bhandari, Rashna
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Science Ltd 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913618/
https://ncbi.nlm.nih.gov/pubmed/27140681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.04.011
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