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Ultrasensitive proteomic quantitation of cellular signaling by digitized nanoparticle-protein counting
Many important signaling and regulatory proteins are expressed at low abundance and are difficult to measure in single cells. We report a molecular imaging approach to quantitate protein levels by digitized, discrete counting of nanoparticle-tagged proteins. Digitized protein counting provides ultra...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4913309/ https://ncbi.nlm.nih.gov/pubmed/27320899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28163 |
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