CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia

In addition to antiplatelet autoantibodies, CD8(+) cytotoxic T lymphocytes (CTLs) play an important role in the increased platelet destruction in immune thrombocytopenia (ITP). Recent studies have highlighted that platelet desialylation leads to platelet clearance via hepatocyte asialoglycoprotein r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qiu, Jihua, Liu, Xuena, Li, Xiaoqing, Zhang, Xu, Han, Panpan, Zhou, Hai, Shao, Linlin, Hou, Yu, Min, Yanan, Kong, Zhangyuan, Wang, Yawen, Wei, Yu, Liu, Xinguang, Ni, Heyu, Peng, Jun, Hou, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913243/
https://ncbi.nlm.nih.gov/pubmed/27321376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27445
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