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Cleavage behavior of calicheamicin gamma 1 and calicheamicin T.

Calicheamicin gamma 1 is a potent antitumor antibiotic that cleaves DNA with a high degree of specificity; there is much interest in the recognition process. We have investigated the DNA-cleaving properties of calicheamicin T, a truncated derivative of calicheamicin. We show that calicheamicin T cle...

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Hlavní autoři: Walker, S, Landovitz, R, Ding, W D, Ellestad, G A, Kahne, D
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC49132/
https://ncbi.nlm.nih.gov/pubmed/1584797
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