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Selective Chemical Genetic Inhibition of Protein Kinase C Epsilon Reduces Ethanol Consumption in Mice

Reducing expression or inhibiting translocation of protein kinase C epsilon (PKCε) prolongs ethanol intoxication and decreases ethanol consumption in mice. However, we do not know if this phenotype is due to reduced PKCε kinase activity or to impairment of kinase-independent functions. In this study...

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Bibliografiske detaljer
Udgivet i:Neuropharmacology
Main Authors: Maiya, Rajani, McMahon, Thomas, Wang, Dan, Kanter, Benjamin, Gandhi, Dev, Chapman, Holly L., Miller, Jacklyn, Messing, Robert O.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912951/
https://ncbi.nlm.nih.gov/pubmed/26947945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.02.036
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