Novel Small Molecule Inhibitors of Protein Kinase C Epsilon Reduce Ethanol Consumption in Mice

BACKGROUND: Despite the high cost and widespread prevalence of alcohol use disorders, treatment options are limited, underscoring the need for new, effective medications. Previous results using protein kinase C epsilon (PKCε) knockout mice, RNA interference against PKCε, and peptide inhibitors of PK...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Blasio, Angelo, Wang, Jingyi, Wang, Dan, Varodayan, Florence P., Pomrenze, Matthew B., Miller, Jacklyn, Lee, Anna M., McMahon, Thomas, Gyawali, Sandeep, Wang, Hua-Yu, Roberto, Marisa, McHardy, Stanton, Pleiss, Michael A., Messing, Robert O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984071/
https://ncbi.nlm.nih.gov/pubmed/29198469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.10.017
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